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    Etiology

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    • Viral: hepatitis B (common), A, D (in presence of B), E (especially in pregnancy), C (rare), HSV, CMV, infectious mononucleosis, parvovirus B19

    • Toxins (predictable): acetaminophen (common), Amanita mushrooms, tetracycline, valproic acid, carbon tetrachloride

    • Toxins (idiosyncratic): INH, NSAIDs, halothane, ecstasy, kava

    • Vascular: right-sided CHF, shock liver, portal vein thrombosis, Budd-Chiari syndrome

    • Metabolic & other: Wilson's disease, acute fatty liver of pregnancy, HELLP syndrome, Reye's syndrome, hyper- or hypothermia, lymphoma

    See related DDx

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