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HIV and AIDS-related Illness

AUTHOR:
Joseph Mort
LEARNING OBJECTIVES:
  1. Explain the lifecycle and mechanism of HIV infection including the cell type infected, important cell surface receptors, and unique molecular machinery used by the virus.
  2. Know the clinical presentation and timing of acute retroviral syndrome.
  3. List surveillance strategies for patients with HIV infection including the relationship between CD4 count and HIV viral load, unique preventative screening, and use of prophylactic antibiotics.
  4. Know how to make the diagnosis of AIDS.
  5. List common opportunistic infections associated with AIDS including Pneumocystis jirovecii pneumonia, candidiasis, Mycobacterium tuberculosis, CMV retinitis, toxoplasmosis, and cryptococcal meningitis. 
  6. List common malignancies associated with AIDS including Kaposi sarcoma, non-Hodgkin lymphoma, primary CNS lymphoma, invasive cervical carcinoma, and anal squamous cell carcinoma.
  7. Understand the concept of highly active antiretroviral therapy (HAART) and know the correct number of medications to use and their mechanism of action.
Chapter
AccessMedicine > Huppert’s Notes: Pathophysiology and Clinical Pearls for Internal Medicine > Diseases & Pathophysiology in Infectious Diseases
Section
AccessMedicine > Huppert’s Notes: Pathophysiology and Clinical Pearls for Internal Medicine > Key Clinical Trials & Publications in Infectious Diseases > HIV/AIDS
Case File
AccessMedicine > Case Files: Family Medicine, 5e > Case 45 > HIV, AIDS, and Other Sexually Transmitted Infections
Case File
AccessMedicine > Pathophysiology of Disease Cases > Case 12 > Acquired Immunodeficiency Syndrome (AIDS)
Case File
AccessMedicine > Vanderbilt Internal Medicine and Pediatric Curriculum > 23 > Human Immunodeficiency Virus
Case File
AccessMedicine > Vanderbilt Internal Medicine and Pediatric Curriculum > 24 > Pre-exposure prophylaxis (PrEP) for HIV
Chapter
AccessMedicine > Harrison's Principles of Internal Medicine, 21e > Human Immunodeficiency Virus Disease: AIDS and Related Disorders

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