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Graft-versus-Host Disease

AUTHOR:
Joseph Mort
LEARNING OBJECTIVES:
  1. List indications for hematopoietic stem cell transplantation (HSCT) and the difference between autologous and allogeneic HSCT.
  2. Recognize interventions when selecting a donor and prior to HSCT that can reduce the risk of GVHD.
  3. Explain the pathogenesis of graph-versus-host disease (GVHD) and identify the cell type responsible for initiating this disorder.
  4. Describe the typical signs and symptoms of acute and chronic GVHD.
  5. Understand the acute treatment and long-term prevention of GVHD after HSCT.
Section
AccessMedicine > Huppert’s Notes: Pathophysiology and Clinical Pearls for Internal Medicine > Key Medications & Interventions in Hematology > STEM CELL TRANSPLANT BASICS
Chapter
AccessMedicine > Hall, Schmidt and Wood’s Principles of Critical Care, 5th Edition > Hematopoietic Stem Cell Transplantation and Graft-Versus-Host Disease
Section
AccessMedicine > The Infographic Guide to Medicine > Hematology/Oncology > Graft vs Host Disease (GVHD)

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